Antifungal Activity Of Java Acid Leaf Ethanol Extract (Tamarindus Indica L.) On Fungi Growth Malassezia Furfur And Trichophyton Mentagrophytes

Abstract

Fungi are heterotrophic organisms that, if alive, can cause disease in plants and animals, including humans. This research was conducted to determine the potential inhibitory power and Minimum Inhibitory Concentration (MIC) of ethanol extract of tamarind leaves against the fungi Malassezia furfur and Tricophyton mentagrophytes and to determine the correlation between antifungal potential and extract concentration. The extraction method uses the maceration method and fungal testing uses the disc diffusion method and data analysis uses ANOVA, correlation, and regression. The results of the analysis of the diameter of the inhibition zone for Malassezia furfur and Trichophyton mentagrophytes obtained a significant value of 0.000 (p<0.05). The optimum inhibitory concentration against Malassezia furfur and Trichophyton mentagrophytes at a concentration of 100 mg/mL is in a strong category. There is a positive relationship between Malassezia furfur and Tricophyton mentagrophyes. The results of linear regression on Malassezia furfur obtained the equation y=0.1068x+3.8004, while Trichophyton mentagrophytes obtained the equation y=0.1258x+3.4978. The results of the ANOVA obtained from the inhibitory power of the two fungi were not significantly different. The ethanol extract of tamarind leaves has antifungal potential and has a close relationship, the effect of extract concentration on Malassezia furfur is 96.66% and Tricophyton mentagrophytes is 96.5%, the inhibitory power of the two fungi is not significantly different