EFFECTIVENESS OF THE COMBINATION OF METFORMIN AND GLIMEPIRIDE AS A LOWERING OF BLOOD GLUCOSE IN PATIENTS WITH DIABETES MELLITUS AT THE UPTD GEMBONG HEALTH CENTER

Abstract

According to Riskesdas (2019), the estimated number of Diabetes Mellitus sufferers in Central Java is 652,822 people with a percentage of 83.1%. Diabetes Mellitus can cause various complications of the disease, so it is necessary to monitor blood glucose levels. Pharmacological therapy used to treat Diabetes Mellitus type 2 is the use of oral antidiabetics alone or in combination. Commonly used oral antidiabetics are metformin and glimepiride. This study aims to describe the effectiveness of using oral antidiabetic drugs in lowering blood glucose in Diabetes Mellitus patients. This research is a quantitative study using a cross-sectional design. This research was conducted prospectively by conducting direct monitoring for a period of 3 months from March 2022 to May 2022 at the UPTD Gembong Health Center, Pati Regency. The sampling technique was carried out by purposive sampling and the research instruments used were data collection sheets and medical records. The data obtained was carried out by observing the effectiveness of the use of oral antidiabetic drugs and data analysis. Most cases in this study were in the female sex group (72.8%), aged 51-60 years (50.0%), and housewives (58.3%). The use of combined oral antidiabetic drugs was more with a percentage of 83.3%. The use of oral antidiabetics can reduce blood glucose levels in Diabetes Mellitus patients. Based on these results it can be concluded that the use of oral antidiabetics for outpatients at the UPTD Gembong Health Center, Pati Regency has effectiveness in reducing blood glucose levels in Diabetes Mellitus patients.