Chemotherapy Adherence as a Determining Factor For Quality Of Life In Cancer Patients

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Published: Sep 30, 2026
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Heriyanti Widyaningsih (*)
Institut Teknologi Kesehatan Cendekia Utama Kudus
widyaningsih.sunarto@gmail.com
Husnul Khotimah
Alvi Ratna Yuliana
Anita Dyah Listyarini
Noor Faidah
Sri Hartini
Biyanti Dwi Winarsih

(*) Corresponding Author

Abstract

Abstract. Cancer is one of the leading causes of mortality worldwide and continues to increase every year. Cancer and its treatment, particularly chemotherapy, play a crucial role in the healing process; however, chemotherapy often leads to adverse side effects that may result in morbidity and decreased quality of life. Patient adherence to chemotherapy has a positive impact on treatment effectiveness and quality of life. Therefore, it is important to determine the relationship between chemotherapy adherence and quality of life among cancer patients in order to improve therapeutic outcomes and patient well-being. This study employed a quantitative research design with a descriptive correlational approach and a cross-sectional method. The study population consisted of cancer patients undergoing chemotherapy from January 2024 to January 2025, totaling 241 patients. A sample of 54 respondents was selected. Chemotherapy adherence was measured using the Morisky Medication Adherence Scale (MMAS), and quality of life was measured using the WHO Quality of Life-BREF (WHOQOL-BREF) questionnaire. Data were analyzed using the Spearman rank correlation test. The results of the Spearman rank test showed a significance value of 0.002 < 0.05, indicating that the alternative hypothesis (Ha) was accepted and the null hypothesis (Ho) was rejected. This demonstrates a positive relationship between chemotherapy adherence and the quality of life of cancer patients. The correlation coefficient was 0.408, indicating a moderate level of association between the two variables.There is a significant relationship between chemotherapy adherence and the quality of life of cancer patients at RSUD RAA Soewondo Pati.

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How to Cite
Widyaningsih, H., Khotimah, H., Yuliana, A. R., Listyarini, A. D., Faidah, N., Hartini, S., & Winarsih, B. D. (2026). Chemotherapy Adherence as a Determining Factor For Quality Of Life In Cancer Patients . Proceeding Cendekia International Conference Health and Technology, 4(2), 415–424. Retrieved from https://proceedings.centamaku.ac.id/article/view/309
Issue
Vol. 4 No. 2 (2026): Interprofessional Collaboration in Integrative Health Approaches for Chronic Disease Management
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Articles

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