ANTIFUNGAL ACTIVITY OF LIQUID SOAP CURLY RED CHILI FRUIT (CAPSICUM ANNUUM L. VAR. LONGUM) EXTRACT AGAINST CANDIDA ALBICANS

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Published: Aug 5, 2024
Keywords:
Antifungal; Curly red chilies; Candida albicans; Liquid soap
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Wara Madia
sugiartililis322@gmail.com
Lilis Sugiarti (*)
Institut Teknologi Kesehatan Cendekia Utama Kudus, Indonesia
sugiartililis322@gmail.com
Mohd Nadzri Mohd Najib
Universiti Teknologi MARA

(*) Corresponding Author

Abstract

Abnormal vaginal discharge can be caused by a Candida albicans fungal infection. Vaginal discharge that is not treated properly can cause infertility. Curly red chili plants have the potential to have antifungal activity because they contain chemical compounds in the form of alkaloids, flavonoids, tannins, saponins and triterpenoids. The aim of this study was to determine the antifungal activity of liquid soap curly red chili fruit (Capsicum annum L. var. longum) extract against Candida albicans. Curly red chili fruit was extracted using the UAE method with 70% ethanol solvent. The extract was formulated into liquid soap with formula 0 (0%), formula 1 (5%) and formula 2 (15%) which was tested against the Candida albicans fungus using the well diffusion method with control (+), namely Resik V Godokan Sirih. The research results showed that liquid soap with extract of curly red chili fruit could inhibit Candida albicans with the diameter of the inhibition zone of formula 0, formula 1 and formula 2 respectively 9.11 ± 0.31 mm (medium); 16.43±0.11mm (strong) and 20.19±0.34mm (strong). Control (+) had an inhibition zone diameter of 32.40 ± 0.59 (very strong). The optimal liquid soap formula for curly red chili fruit extract (Capsicum annum L. var. longum) in inhibiting Candida albicans is formula 2.

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How to Cite
Wara Madia, Lilis Sugiarti, & Najib, M. N. M. (2024). ANTIFUNGAL ACTIVITY OF LIQUID SOAP CURLY RED CHILI FRUIT (CAPSICUM ANNUUM L. VAR. LONGUM) EXTRACT AGAINST CANDIDA ALBICANS. Proceeding Cendekia International Conference Health and Technology, 2, 216–221. Retrieved from https://proceedings.centamaku.ac.id/article/view/115
Issue
Vol. 2 (2024): Pain Management Approaches in Palliative Care
Section
Articles
Author Biography

Mohd Nadzri Mohd Najib, Universiti Teknologi MARA

Faculty of Pharmacy, Universiti Teknologi MARA, Cawangan Pulau Pinang, Kampus Bertam, 13200 Kepala Batas, Malaysia

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