The Differences In Quality Of Life Of Early And Advanced Cervical Cancer Patients At Dr. Sardjito Hospital Yogyakarta, Indonesia

Abstract

Background: Early detection of cervical cancer which is increasingly developing causes cancer patients to survive longer and the side effects of cervical cancer therapy will have long-term effects so that the quality of life of cancer patients is an important thing

Methods: The population was all suffer from cervical cancer who were undergoing a chemotherapy program at RSUP DR. Sardjito Yogyakarta in October - November 2017 using a purposive sampling technique with 62 respondents, 18 groups of early stages, and 44 advanced stages. This study uses family support instruments, the Indonesian version of the EORTC QLQ-C30, and the translated EORTC QLQ-C24 which has validity and reliability. Patients were measured on quality of life at the moment of chemotherapy.

Results: Quality of life for cervical cancer patients with early and advanced stages on health in general status (quality of life) and the function scale the mean value is >50 with the largest mean value at the early stage, which means that the early stage has a higher quality of life and better function with significant differences on physical function (p=0.003), role function (p=0.002), and social function (p=0.012) where p<0.05. For the symptom scale, the highest average score is almost all in the advanced stage with the highest score in financial difficulties with an average value of 57.58 ± 44.527 and the smallest value in dyspnea with an average value of 8.33 ± 22.875, except for dyspnea the largest value is in the early stages with an average 20.37 ± 23.260 vs. 8.33 ± 22.875. Significant differences in the symptom scale were found in fatigue with a value of p=0.040 and pain p=0.010.

      On the EORTC QLQ-CX24, the multi-item and single-item scales have the greatest value at an advanced stage, except for the single-item scale, sexual anxiety is greater at the early stage with the highest score on peripheral neuropathy at 39.39 ± 44.474 and the lowest value on the sexual activity at the advanced stage. initial 1.85 ± 7.857 withouth statistically significant in difference (p>0.05)

In Conclusion there is a significant difference between the quality of life of early and advanced cervical cancer patients where the early stage has a better quality of life in terms of physical function, role function, social function, fatigue, and pain with a value of p> 0.05.