Testing The Antiacne Activity Of Mangostan (Garcinia Manggostana L.) Skin Extract Cream On Propionibacterium Acnes

Abstract

The face is the part of the head that is often contaminated by bacteria. One way to get rid of bacteria on the face is to use acne cream. Mangosteen rind has antibacterial activity, mangosteen rind can be used as an acne cream preparation. This type of research is experimental by testing mangosteen rind extract using the well method against Propionibacterium acne bacteria to find out whether mangosteen rind extract has antibacterial activity, making a concentration series of 5 grams, 10 grams, 15 grams as a formula for preparing mangosteen rind extract acne cream. will be tested against Propionibacterium acne. The best concentration of mangosteen rind extract against Propionibacterium acne bacteria with a concentration of 25 mg/ml in 3 replications obtained the greatest inhibitory power of 1.6 cm of mangosteen rind extract on Propiobibacterium acne bacteria. Meanwhile, the inhibitory power obtained in the cream preparation was formulation III, namely 2.9 cm on the propionibacterium acne bacteria. Mangosteen rind extract cream preparation can inhibit Propionibacterium acne bacteria. The test result data was analyzed statistically if the data was normal using one way ANOVA and if it was not normal using the Kruskal-Wallis and Mann-Whitney tests.